Around nine out of every ten drug candidates fail to win approval, with huge implications for the overall cost of drug development. But what drives these failure rates, and how can the pharma industry improve productivity when moving drug candidates from the laboratory to the clinic?
Most people who have a passing association with the pharmaceutical business will be able to give a rough estimate of how much it costs to take a drug candidate through clinical trials and regulatory approval. The estimate would likely be based on something like the Tufts Center for the Study of Drug Development’s (CSDD) regular assessment of drug development costs, the latest of which pegged the average cost of reaching marketing approval at just under $2.6bn.
This article highlights the scope for developing therapeutics with new innovative, alternative approaches. The current trillion dollars pharmaceutical industry is in peril where the current drug development pipeline is slow, inefficient and incapable of being extended to multi-combination drug therapies as well as minimally focused on prevention. The complex modeling of diseases and biological functions has been limited because of the inability to integrate large scale molecular pathways.
Watch this Video to understand how recent advances provide breakthrough technology for doing scalable modeling of complex molecular systems to dramatically accelerate drug discovery and development.