CytoSolve - The 23rd Century Platform for Discovery

CytoSolve Collaborates With World-Renowned Scientists at Leading Universities, Research Institutions and Foundations to Develop and Validate Large-Scale Systems Architecture and Models of Disease and Complex Biological Phenomena.


The Future of Health

American Society for Clinical Pharmacology and Therapeutics (ASCPT) Honors Dr. Shiva Ayyadurai and the Development of CytoSolve.


Pericytes of the Neurovascular Unit: Key Functions and Signaling Pathways

Download this pioneering research paper published in the peer-reviewed journal Nature Neuroscience, that uses the CytoSolve approach to create a novel systems architecture of the neurovascular unit to examine the key signaling pathways between pericytes and their neighboring endothelial cells, astrocytes and neurons that control neurovascular functions. This pioneering work provides novel insights into the role of pericytes in central nervous system disorders including rare monogenic diseases and complex neurological disorders such as Alzheimer’s disease and brain tumors.

Please submit the form below to download the research paper. The download link will be sent to your email address.

Our Chairman & CEO

Dr. Shiva Ayyadurai

Dr. Shiva Ayyadurai, the Founder and CEO of CytoSolve, Inc., is the Inventor of Email and holds 4 degrees from MIT. He is a Fulbright Scholar and has started 7 successful hi-tech companies including EchoMail, CytoSolve and Systems Health. He is also the Founder of Center for Integrative Systems that performs fundamental research in systems thinking and is the home of Innovation Corps and C.L.E.A.N./R.A.W. certifications. He is now a candidate for US Senate from Massachusetts.