The blood-brain barrier is a protective layer that surrounds the brain. Its main function is to prevent potentially harmful agents from leaking into this organ. However, it can also stop certain therapeutic drugs from reaching their target.
The blood-brain barrier prevents antitumor drugs and those that fight the symptoms of neurological conditions such as Alzheimer’s disease from reaching the brain and doing their work.
Scientists can address this issue by temporarily bypassing the blood-brain barrier by using low-frequency ultrasound pulses.
This article highlights the scope for developing therapeutics with new innovative, alternative approaches. The current trillion dollars pharmaceutical industry is in peril where the current drug development pipeline is slow, inefficient and incapable of being extended to multi-combination drug therapies as well as minimally focused on prevention. The complex modeling of diseases and biological functions has been limited because of the inability to integrate large scale molecular pathways.
Watch this Video to understand how recent advances provide breakthrough technology for doing scalable modeling of complex molecular systems to dramatically accelerate drug discovery and development.