CytoSolve® and Wapiti Labs built a systems architecture linking Elk Velvet Antler bioactives to seventeen biological functions and health mechanisms.

Wapiti Labs is a science-oriented nutraceutical organization focused on advancing evidence-based understanding of traditional and nature-derived bioactives. To strengthen scientific rigor and support future regulatory and product development initiatives, Wapiti Labs partnered with CytoSolve® to apply a structured systems architecture methodology to Elk Velvet Antler—moving beyond descriptive claims toward an integrated, literature-grounded biological framework.

Challenge

Elk Velvet Antler has a long history of traditional use and a growing body of scientific literature describing diverse health benefits. However, several challenges limited translational and regulatory utility:

Scientific evidence was fragmented across disciplines and databases

Bioactive compounds were studied in isolation without an integrated systems view

Health effects spanned multiple physiological domains, complicating interpretation

Lack of a unified architecture linking nutrition → molecular mechanisms → biological functions

Wapiti Labs required a systematic, reproducible method to organize existing knowledge into a coherent systems-level representation.

How CytoSolve® Helped

CytoSolve® applied its systems architecture and bioinformatics methodology to construct a comprehensive scientific framework for Elk Velvet Antler:

Parallel Literature Mining and Precision Filtering

Conducted a broad literature search across PubMed, Google Scholar, and ScienceDirect, yielding an initial corpus of 82 peer-reviewed publications.

Applied parallel precision search criteria constrained to:

  • Elk Velvet Antler composition
  • Neurodegeneration
  • Osteoarthritis and rheumatoid arthritis
  • Liver health
  • Inflammation
  • Muscle promotion
  • Sexual health
  • Immune modulation
Filtered the initial corpus to a relevant, high-confidence literature set based on titles and abstracts.

Expert-Guided Systems Review

  • Domain experts reviewed the curated literature set using the CytoSolve® user interface.
  • Identified nutritional components, active compounds, and documented biological effects.
  • Mapped relationships between bioactives and downstream biological functions.
Systems Architecture Construction

Applied a structured bioinformatics workflow:

  • Aggregation of literature from disparate sources.
  • Identification and validation of relevant studies.
  • Extraction of nutritional profiles and active compounds.
  • Mapping of compounds to biological processes and health domains.
Built a systems architecture demonstrating how Elk Velvet Antler bioactives influence seventeen biological functions.

Mechanistic Domain Mapping

Where supported by literature, CytoSolve® documented mechanisms of action linking Elk Velvet Antler bioactives to:

  • Neurodegeneration pathways.
  • Osteoarthritis and rheumatoid arthritis.
  • Immunomodulatory signaling.
  • Inflammatory regulation.
  • Liver health and metabolic support.

Key Benefits Realized

  • Systems-Level Clarity – Unified fragmented literature into a coherent biological architecture.
  • Multi-Domain Coverage – Captured effects across neurological, musculoskeletal, immune, and hepatic systems.
  • Scientific Traceability – All architectural elements grounded in peer-reviewed literature.
  • Regulatory Readiness – Structured evidence suitable for government, quality, and compliance review.
  • Model-Ready Foundation – Architecture can be extended into quantitative in silico simulations.

Outcome

The CytoSolve® systems architecture study provided Wapiti Labs with a comprehensive, literature-grounded framework describing how Elk Velvet Antler bioactive compounds influence a wide spectrum of biological functions. By identifying nutritional components, mapping documented mechanisms of action, and organizing effects across seventeen physiological domains, this work establishes a defensible scientific foundation for future computational modeling, regulatory filings, and evidence-based product development. The case study demonstrates how CytoSolve® transforms complex, multidisciplinary nutrition science into an integrated systems architecture aligned with modern scientific and regulatory expectations.