Our Partners and Collaborations Validating Our Platform

Our Partners - world-class research institutions, leading pharmaceutical and nutraceutical manufacturers - supported the validation of CytoSolve® - the infrastructure for computational systems biology to discover safe and synergistic multi-combination therapeutics, without animal testing

Systems
Architecture ​

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Global Genes gained systems-level insights into hidden gene interconnections across rare diseases, inspiring unified, mechanism-driven research and advocacy strategies.

Systems
Architecture ​

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Stanford’s Sakamoto Lab in collaboration with CytoSolve® created the first full-scale systems architecture of AML, revealing hidden pathway interconnections and novel therapeutic targets.

Systems
Architecture ​

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Forsyth Institute in collaboration with CytoSolve® created the first full-scale systems architecture of Periodontitis, revealing hidden pathway interconnections and novel oral microbiome therapeutic targets.

Systems
Architecture ​

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MIT’s Kamm Lab in collaboration with CytoSolve® built the first systems architecture of ALS neuromuscular junction microenvironment, revealing hidden mechanobiological drivers.

Peer- Reviewed
Validation​

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USC Keck School of Medicine completed peer-reviewed validation of CytoSolve’s pericytes systems architecture, resulting in major Nature Neuroscience publication.

Peer- Reviewed
Validation​

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University of Toronto’s Keating Lab completed peer-reviewed validation of CytoSolve’s MSC microenvironment architecture, published in Oxford University Press journal.

Peer- Reviewed
Validation​

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MIT’s Dewey Lab completed peer-reviewed validation of CytoSolve’s nitric oxide model, published in Cell’s Biophysical Journal.


Peer- Reviewed
Validation​

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Tufts School of Medicine completed peer-reviewed validation of CytoSolve’s low-grade chronic inflammation models, published in Clinical Nutrition ESPEN.

In-Silico
Modeling

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CytoSolve’s in silico model quantifies vascular endothelial nitric oxide regulation under shear stress, integrating multiple molecular pathways.

In-Silico
Modeling

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CytoSolve’s in silico modeling revealed how D-glucaric acid mechanistically enhances liver detoxification through integrated, systems-level molecular pathway analysis.

In-Silico
Modeling

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CytoSolve’s in silico modeling demonstrated how ClearLungs® ingredients synergistically alleviate lung congestion through inflammation, mucus regulation, and smooth muscle relaxation.

In-Silico
Modeling

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CytoSolve’s in silico modeling revealed how SeaMeal™ ingredients synergistically improve pet coat appearance through skin barrier synthesis and oxidative stress reduction.

Ingredient
Analysis

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CytoSolve’s in silico analysis mapped black cumin seed bioactives to key molecular pathways underlying inflammation, oxidative stress, and metabolic regulation.

Ingredient
Analysis

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CytoSolve’s in silico analysis quantified how sprouting alters bioactive compound potency and pathway engagement versus raw and roasted ingredients.

Ingredient
Analysis

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CytoSolve’s bioinformatics modeling revealed how oat-derived compounds modulate molecular systems governing relaxation and fatigue through validated, systems-level mechanisms.

Ingredient
Analysis

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CytoSolve’s in silico modeling validated the potency and efficacy of D-glucaric acid across molecular pathways governing detoxification and cellular protection.

Combination
Screening

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CytoSolve’s in silico combination screening demonstrated synergistic joint health benefits of multi-ingredient equine formulations across inflammation, oxidative stress, and cartilage pathways.

Combination
Screening

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The Natural Vet and CytoSolve® validated Redoxx® and Bug Check™ using computational screening to prove cellular energy and repellent efficacy.

Combination
Screening

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British American Tobacco and CytoSolve® used computational modeling to analyze how bioactive ingredients affect molecular pathways to promote relaxation and stress-relief.

Combination
Screening

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Life Extension and CytoSolve® used computational modeling to discover and optimize three plant-based formulations designed to boost human testosterone levels.

Government
Filings

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Ramard and CytoSolve® used computational modeling to prove their Joint Pain Formula's synergistic effects, providing scientific evidence for patent protection.

Government
Filings

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ICIS uses CytoSolve’s computational platform to validate safety, processing, and bioavailability for Certified C.L.E.A.N.® and Certified R.A.W.® food standards.

Government
Filings

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Juice Plus+ and CytoSolve® used computational modeling to prove how phytonutrient blends synergistically reduce chronic inflammation for regulatory and government filings.

Government
Filings

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CytoSolve® and the FDA identified Cyto-001, a low-toxicity drug combination for pancreatic cancer, using computational models to prove enhanced apoptosis.

Commercialization

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CytoSolve® partnered with Wapiti Labs to computationally validate Elk Velvet Antler health benefits, enabling evidence-based commercialization through large-scale systems bioinformatics.

Commercialization

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CytoSolve® partnered with Alnylam to computationally model HAE contact activation pathways, predicting siRNA target-response relationships and accelerating RNAi therapeutic strategies.

Commercialization

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CytoSolve® modeled gut motility pathways to mechanistically validate Actazin™ and Livaux™, enabling evidence-based commercialization of digestive health supplements through systems.

Commercialization

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CytoSolve® enabled British American Tobacco to mechanistically validate relaxation-focused ingredients through systems-level modeling of stress-regulating molecular pathways.