Probiotic Supplements Show No Benefit for Children with Gastroenteritis

Source: Contagion Live

The results of a new pair of studies from investigators in the United States and Canada have debunked a previously accepted idea that probiotic supplements are helpful to children with gastroenteritis.

Gastroenteritis leads to 1.7 million pediatric emergency room visits and more than 70,000 hospitalizations in the United States each year. Treatment for these infections typically includes replacing lost fluids and electrolytes; however, previous research has indicated that treatment for healthy infants and children can include supplementation with probiotics, to reduce the severity and duration of symptoms by restoring normal bacterial microflora in the gastrointestinal tract.

Now, investigators on the pair of studies, published in the New England Journal of Medicine, found that probiotic supplements were ineffective at reducing diarrhea and vomiting in children with gastroenteritis.

read more..

This article highlights the scope for developing therapeutics with new innovative, alternative approaches. The current trillion dollars pharmaceutical industry is in peril where the current drug development pipeline is slow, inefficient and incapable of being extended to multi-combination drug therapies as well as minimally focused on prevention. The complex modeling of diseases and biological functions has been limited because of the inability to integrate large scale molecular pathways.

Watch this Video to understand how recent advances provide breakthrough technology for doing scalable modeling of complex molecular systems to dramatically accelerate drug discovery and development.

Cytosolve On Twitter