A Distributed Computational Architecture for Integrating Multiple Biomolecular Pathways
V. A. SHIVA AYYADURAI and C. FORBES DEWEY, JR.
Biomolecular pathways are building blocks of cellular biochemical function. Computational biology is in rapid transition from diagrammatic representation of pathways to quantitative and predictive mathematical models, which span time-scales, knowledge domains and spatial-scales. This transition is being accelerated by high-throughput experimentation which isolates reactions and their corresponding rate constants.